Frequency of primary glomerular disease in northeastern China

• Main Authors: Yi-Qi Wu, Zheng Wang, Hua-Feng Xu, Xiao-Ming Jin, Hai-Zhou Zhou
• Format: Article
• Language: English
• Published: Associação Brasileira de Divulgação Científica 2011-08-01
• Series: Brazilian Journal of Medical and Biological Research
• Subjects: Primary glomerular disease; Renal biopsies; IgA nephropathy; China
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000800011

Most frequently reported Chinese renal biopsy data have originated from southeastern China. The present study analyzed the renal biopsy data from northeastern China. The records of 1550 consecutive native patients who were diagnosed with primary glomerular diseases (PGD) after renal biopsy at our hospital during 2005-2009 were used. These patients were divided into four age groups for stratified analysis: <15, 15-44, 45-59, and &#8805;60 years old. Among PGD, minimal change disease (MCD) was the most common histologically diagnosed disease (30.7%), followed by IgA nephropathy (IgAN), mesangial proliferative glomerulonephritis (MsPGN), membranous nephropathy (MN), membranoproliferative glomerulonephritis (MPGN), focal segmental glomerulosclerosis (FSGS), and endocapillary proliferative glomerulonephritis (EnPGN). MCD was the disease most frequently observed (43.7%) in the <15-year-old group. MsPGN was the most common disease in the elderly group (38.1%). MsPGN was more prevalent in females (27.8%), whereas MCD was more prevalent in males (35.3%). Primary glomerular diseases constituted the most commonly encountered group of diseases with a high prevalence of MCD, which predominantly affected males and young adults. The prevalence of MCD was high in northeastern China. Further study is necessary to expand the epidemiologic data available for renal disease in China.