Synthesis of Tilmicosin Nanostructured Lipid Carriers for Improved Oral Delivery in Broilers: Physiochemical Characterization and Cellular Permeation

Synthesis of Tilmicosin Nanostructured Lipid Carriers for Improved Oral Delivery in Broilers: Physiochemical Characterization and Cellular Permeation

This study aimed to develop nanostructured lipid carriers (NLCs) for improved oral absorption of tilmicosin (TMS) in broilers. Thus, palmitic acid, lauric acid, and stearic acid were selected as solid lipids to formulate TMS-pNLCs, TMS-lNLCs, and TMS-sNLCs, respectively. They showed similar physicoc...

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Bibliographic Details
Main Authors: Benazir Sahito, Qian Zhang, Haifeng Yang, Lin Peng, Xiuge Gao, Jam Kashif, Zain ul Aabdin, Shanxiang Jiang, Liping Wang, Dawei Guo
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
tilmicosin
nanostructured lipid carriers
oral bioavailability
broiler
cellular permeability
p-gp efflux
Online Access:https://www.mdpi.com/1420-3049/25/2/315

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https://www.mdpi.com/1420-3049/25/2/315

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