Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange

We report a case of a bodybuilder who took a regimen of anabolic steroids containing stanozolol and testosterone propionate for 8 weeks which led to the development of jaundice and severe pruritus with serum total bilirubin reaching 41.22 mg/dL. Despite supportive care with fluid and albumin therapy...

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Main Authors: Christelle El Khoury, Toni Sabbouh, Hussein Farhat, Antoine Ferzli
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2017/4296474
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spelling doaj-9c1aa056a7d343d69601f6a94ff3154a2020-11-24T22:29:04ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352017-01-01201710.1155/2017/42964744296474Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma ExchangeChristelle El Khoury0Toni Sabbouh1Hussein Farhat2Antoine Ferzli3Family Medicine Division, Lebanese American University Medical Center, Beirut, LebanonInternal Medicine Division, Morristown Medical Center, Morristown, NJ, USALaboratory Medicine Division, Lebanese American University Medical Center, Beirut, LebanonGastroenterology Division, Lebanese American University Medical Center, Beirut, LebanonWe report a case of a bodybuilder who took a regimen of anabolic steroids containing stanozolol and testosterone propionate for 8 weeks which led to the development of jaundice and severe pruritus with serum total bilirubin reaching 41.22 mg/dL. Despite supportive care with fluid and albumin therapy, serum creatinine was progressively increasing. He underwent 6 successful sessions of plasma exchange (PE) with marked improvement at the end of the sessions. Three months after discharge, the patient’s creatinine and total bilirubin levels were 1.08 mg/dL and 1.2 mg/dL, respectively.http://dx.doi.org/10.1155/2017/4296474
collection DOAJ
language English
format Article
sources DOAJ
author Christelle El Khoury
Toni Sabbouh
Hussein Farhat
Antoine Ferzli
spellingShingle Christelle El Khoury
Toni Sabbouh
Hussein Farhat
Antoine Ferzli
Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange
Case Reports in Medicine
author_facet Christelle El Khoury
Toni Sabbouh
Hussein Farhat
Antoine Ferzli
author_sort Christelle El Khoury
title Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange
title_short Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange
title_full Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange
title_fullStr Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange
title_full_unstemmed Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange
title_sort severe cholestasis and bile cast nephropathy induced by anabolic steroids successfully treated with plasma exchange
publisher Hindawi Limited
series Case Reports in Medicine
issn 1687-9627
1687-9635
publishDate 2017-01-01
description We report a case of a bodybuilder who took a regimen of anabolic steroids containing stanozolol and testosterone propionate for 8 weeks which led to the development of jaundice and severe pruritus with serum total bilirubin reaching 41.22 mg/dL. Despite supportive care with fluid and albumin therapy, serum creatinine was progressively increasing. He underwent 6 successful sessions of plasma exchange (PE) with marked improvement at the end of the sessions. Three months after discharge, the patient’s creatinine and total bilirubin levels were 1.08 mg/dL and 1.2 mg/dL, respectively.
url http://dx.doi.org/10.1155/2017/4296474
work_keys_str_mv AT christelleelkhoury severecholestasisandbilecastnephropathyinducedbyanabolicsteroidssuccessfullytreatedwithplasmaexchange
AT tonisabbouh severecholestasisandbilecastnephropathyinducedbyanabolicsteroidssuccessfullytreatedwithplasmaexchange
AT husseinfarhat severecholestasisandbilecastnephropathyinducedbyanabolicsteroidssuccessfullytreatedwithplasmaexchange
AT antoineferzli severecholestasisandbilecastnephropathyinducedbyanabolicsteroidssuccessfullytreatedwithplasmaexchange
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