BEExact: a Metataxonomic Database Tool for High-Resolution Inference of Bee-Associated Microbial Communities

The failure of current universal taxonomic databases to support the rapidly expanding field of bee microbiota research has led to many investigators relying on “in-house” reference sets or manual classification of sequence reads (usually based on BLAST searches), often with vague identity...

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Bibliographic Details
Main Authors: Brendan A. Daisley, Gregor Reid
Format: Article
Language:English
Published: American Society for Microbiology 2021-04-01
Series:mSystems
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00082-21
Description
Summary:The failure of current universal taxonomic databases to support the rapidly expanding field of bee microbiota research has led to many investigators relying on “in-house” reference sets or manual classification of sequence reads (usually based on BLAST searches), often with vague identity thresholds and subjective taxonomy choices. This time expensive, error- and bias-prone process lacks standardization, cripples the potential for comparative cross-study analysis, and in many cases is likely to sway study conclusions.
ISSN:2379-5077