Advances in drug delivery system for platinum agents based combination therapy

Platinum-based anticancer agents are widely used as first-line drugs in cancer chemotherapy for various solid tumors. However, great side effects and occurrence of resistance remain as the major drawbacks for almost all the platinum drugs developed. To conquer these problems, new strategies should b...

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Main Authors:	Xiang Kang, Hai-Hua Xiao, Hai-Qin Song, Xia-Bin Jing, Le-San Yan, Ruo-Gu Qi
Format:	Article
Language:	English
Published:	China Anti-Cancer Association 2015-12-01
Series:	Cancer Biology & Medicine
Subjects:	Cancer drug delivery combination therapy platinum
Online Access:	http://www.cancerbiomed.org/index.php/cocr/article/view/890

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spelling	doaj-9c058ce4c02446b3ad107f2490224a742020-11-24T21:55:17ZengChina Anti-Cancer AssociationCancer Biology & Medicine2095-39412095-39412015-12-0112436237410.7497/j.issn.2095-3941.2015.00632015000063Advances in drug delivery system for platinum agents based combination therapyXiang Kang0Hai-Hua Xiao1Hai-Qin Song2Xia-Bin Jing3Le-San Yan4Ruo-Gu Qi5Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China;State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China;Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China;State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China;State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China;Platinum-based anticancer agents are widely used as first-line drugs in cancer chemotherapy for various solid tumors. However, great side effects and occurrence of resistance remain as the major drawbacks for almost all the platinum drugs developed. To conquer these problems, new strategies should be adopted for platinum drug based chemotherapy. Modern nanotechnology has been widely employed in the delivery of various therapeutics and diagnostic. It provides the possibility of targeted delivery of a certain anticancer drug to the tumor site, which could minimize toxicity and optimize the drug efficacy. Here, in this review, we focused on the recent progress in polymer based drug delivery systems for platinum-based combination therapy.http://www.cancerbiomed.org/index.php/cocr/article/view/890Cancerdrug deliverycombination therapyplatinum
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Xiang Kang Hai-Hua Xiao Hai-Qin Song Xia-Bin Jing Le-San Yan Ruo-Gu Qi
spellingShingle	Xiang Kang Hai-Hua Xiao Hai-Qin Song Xia-Bin Jing Le-San Yan Ruo-Gu Qi Advances in drug delivery system for platinum agents based combination therapy Cancer Biology & Medicine Cancer drug delivery combination therapy platinum
author_facet	Xiang Kang Hai-Hua Xiao Hai-Qin Song Xia-Bin Jing Le-San Yan Ruo-Gu Qi
author_sort	Xiang Kang
title	Advances in drug delivery system for platinum agents based combination therapy
title_short	Advances in drug delivery system for platinum agents based combination therapy
title_full	Advances in drug delivery system for platinum agents based combination therapy
title_fullStr	Advances in drug delivery system for platinum agents based combination therapy
title_full_unstemmed	Advances in drug delivery system for platinum agents based combination therapy
title_sort	advances in drug delivery system for platinum agents based combination therapy
publisher	China Anti-Cancer Association
series	Cancer Biology & Medicine
issn	2095-3941 2095-3941
publishDate	2015-12-01
description	Platinum-based anticancer agents are widely used as first-line drugs in cancer chemotherapy for various solid tumors. However, great side effects and occurrence of resistance remain as the major drawbacks for almost all the platinum drugs developed. To conquer these problems, new strategies should be adopted for platinum drug based chemotherapy. Modern nanotechnology has been widely employed in the delivery of various therapeutics and diagnostic. It provides the possibility of targeted delivery of a certain anticancer drug to the tumor site, which could minimize toxicity and optimize the drug efficacy. Here, in this review, we focused on the recent progress in polymer based drug delivery systems for platinum-based combination therapy.
topic	Cancer drug delivery combination therapy platinum
url	http://www.cancerbiomed.org/index.php/cocr/article/view/890
work_keys_str_mv	AT xiangkang advancesindrugdeliverysystemforplatinumagentsbasedcombinationtherapy AT haihuaxiao advancesindrugdeliverysystemforplatinumagentsbasedcombinationtherapy AT haiqinsong advancesindrugdeliverysystemforplatinumagentsbasedcombinationtherapy AT xiabinjing advancesindrugdeliverysystemforplatinumagentsbasedcombinationtherapy AT lesanyan advancesindrugdeliverysystemforplatinumagentsbasedcombinationtherapy AT ruoguqi advancesindrugdeliverysystemforplatinumagentsbasedcombinationtherapy
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Advances in drug delivery system for platinum agents based combination therapy

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