Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes

Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes

Mesenchymal stromal cells (MSCs) based therapy is a promising approach to treat inflammatory disorders. However, therapeutic effect is not always achieved. Thus the mechanism involved in inflammation requires further elucidation. To explore the mechanisms by which MSCs respond to inflammatory stimul...

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Bibliographic Details
Main Authors: Yaozhen Chen, Xiangyang Qin, Qunxing An, Jing Yi, Fan Feng, Dandan Yin, Ning An, Zheng Liu, Lihong Weng, Shouwen Chen, Xingbin Hu, Wen Yin
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418301877

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