Influence of xanthine oxidoreductase inhibitor, topiroxostat, on body weight of diabetic obese mice

Abstract Plasma xanthine oxidoreductase (XOR) activity is high in metabolic disorders such as diabetic mellitus, obesity, or overweight. Thus, this study investigated whether the XOR inhibitor, topiroxostat, affected body weight. Male db/db mice were fed standard diets with or without topiroxostat f...

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Bibliographic Details
Main Authors: Takashi Nakamura, Mai Nampei, Takayo Murase, Etsuko Satoh, Seigo Akari, Noriaki Katoh, Hiroki Mizukami
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Nutrition & Diabetes
Online Access:https://doi.org/10.1038/s41387-021-00155-2