TIM-3 is not essential for development of airway inflammation induced by house dust mite antigens

TIM-3 is not essential for development of airway inflammation induced by house dust mite antigens

Background: T cell immunoglobulin domain and mucin domain-containing molecule 3 (TIM-3), which is preferentially expressed on Th1 cells rather than Th2 cells, is considered to be a negative regulator of Th1 cell function. This suggests that TIM-3 indirectly enhances Th2-type immune responses by supp...

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Bibliographic Details
Main Authors: Yoshihisa Hiraishi, Aya Nambu, Akiko Shibui, Wakako Nakanishi, Sachiko Yamaguchi, Hideaki Morita, Motoyasu Iikura, Andrew N.J. McKenzie, Kenji Matsumoto, Katsuko Sudo, Tatsuya Yamasoba, Takahide Nagase, Susumu Nakae
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Allergology International
Subjects:
Allergy
Asthma
House dust mite
Mouse
TIM-3
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893016300454

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http://www.sciencedirect.com/science/article/pii/S1323893016300454

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