DNA–protein crosslink proteases in genome stability
DNA–protein crosslink (DPC) proteases digest the protein component of crosslinks that otherwise can cause genomic instability and disease. Ruggiano and Ramadan discuss recent insights into the roles of DPC proteases in the repair of DPCs and beyond.
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-020-01539-3 |
Summary: | DNA–protein crosslink (DPC) proteases digest the protein component of crosslinks that otherwise can cause genomic instability and disease. Ruggiano and Ramadan discuss recent insights into the roles of DPC proteases in the repair of DPCs and beyond. |
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ISSN: | 2399-3642 |