Tanshinone I Inhibits Oxidative Stress–Induced Cardiomyocyte Injury by Modulating Nrf2 Signaling

Tanshinone I Inhibits Oxidative Stress–Induced Cardiomyocyte Injury by Modulating Nrf2 Signaling

Cardiovascular disease, a disease caused by many pathogenic factors, is one of the most common causes of death worldwide, and oxidative stress plays a major role in its pathophysiology. Tanshinone I (Tan I), a natural compound with cardiovascular protective effects, is one of the main active compoun...

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Bibliographic Details
Main Authors: Yu-Ting Wu, Ling-Peng Xie, Yue Hua, Hong-Lin Xu, Guang-Hong Chen, Xin Han, Zhang-Bin Tan, Hui-Jie Fan, Hong-Mei Chen, Jun Li, Bin Liu, Ying-Chun Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
Tanshinone I
oxidative stress
cardiomyocytes
apoptosis
Nrf2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.644116/full

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