Electrospun fibers enhanced the paracrine signaling of mesenchymal stem cells for cartilage regeneration

Electrospun fibers enhanced the paracrine signaling of mesenchymal stem cells for cartilage regeneration

Abstract Background Secretome profiles of mesenchymal stem cells (MSCs) are reflective of their local microenvironments. These biologically active factors exert an impact on the surrounding cells, eliciting regenerative responses that create an opportunity for exploiting MSCs towards a cell-free the...

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Bibliographic Details
Main Authors: Nurul Dinah Kadir, Zheng Yang, Afizah Hassan, Vinitha Denslin, Eng Hin Lee
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Fiber orientation
Paracrine signaling
Mechanotransduction pathway
Cartilage repair
Online Access:https://doi.org/10.1186/s13287-021-02137-8

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