ULTRASTRUCTURAL STUDY ON TISSUE ALTERATIONS CAUSED BY TRYPANOSOMATIDS IN EXPERIMENTAL MURINE INFECTIONS

ULTRASTRUCTURAL STUDY ON TISSUE ALTERATIONS CAUSED BY TRYPANOSOMATIDS IN EXPERIMENTAL MURINE INFECTIONS

The ultrastructural study in different tissues of mice experimentally infected with isolates of Trypanosoma evansi, Trypanosoma cruzi and Leishmania mexicana reveals changes in cardiac myocytes, skeletal muscle fibers and hepatic, adrenal, kidney and spleen cells. Some were cytoarchitectural changes...

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Main Authors: Héctor José Finol, Antonio eRoschman-Gonzalez
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Public Health
Subjects:
Pathology
Ultraestructure
Murine Tissues
Experimental Infections
Trypanosomatids
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpubh.2014.00075/full
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spelling doaj-9bea565aa5784bccb2851bc80890c7db2020-11-24T22:52:06ZengFrontiers Media S.A.Frontiers in Public Health2296-25652014-07-01210.3389/fpubh.2014.0007591270ULTRASTRUCTURAL STUDY ON TISSUE ALTERATIONS CAUSED BY TRYPANOSOMATIDS IN EXPERIMENTAL MURINE INFECTIONSHéctor José Finol0Antonio eRoschman-Gonzalez1Central University of VenezuelaCentral University of VenezuelaThe ultrastructural study in different tissues of mice experimentally infected with isolates of Trypanosoma evansi, Trypanosoma cruzi and Leishmania mexicana reveals changes in cardiac myocytes, skeletal muscle fibers and hepatic, adrenal, kidney and spleen cells. Some were cytoarchitectural changes and other consisted of necrosis. Alterations were also found in microvasculature.The mononuclear cell infiltrate included neutrophils, eosinophils and macrophages. This work shows that various mice tissues are important target for trypanosomatids.http://journal.frontiersin.org/Journal/10.3389/fpubh.2014.00075/fullPathologyUltraestructureMurine TissuesExperimental InfectionsTrypanosomatids
collection DOAJ
language English
format Article
sources DOAJ
author Héctor José Finol
Antonio eRoschman-Gonzalez
spellingShingle Héctor José Finol
Antonio eRoschman-Gonzalez
ULTRASTRUCTURAL STUDY ON TISSUE ALTERATIONS CAUSED BY TRYPANOSOMATIDS IN EXPERIMENTAL MURINE INFECTIONS
Frontiers in Public Health
Pathology
Ultraestructure
Murine Tissues
Experimental Infections
Trypanosomatids
author_facet Héctor José Finol
Antonio eRoschman-Gonzalez
author_sort Héctor José Finol
title ULTRASTRUCTURAL STUDY ON TISSUE ALTERATIONS CAUSED BY TRYPANOSOMATIDS IN EXPERIMENTAL MURINE INFECTIONS
title_short ULTRASTRUCTURAL STUDY ON TISSUE ALTERATIONS CAUSED BY TRYPANOSOMATIDS IN EXPERIMENTAL MURINE INFECTIONS
title_full ULTRASTRUCTURAL STUDY ON TISSUE ALTERATIONS CAUSED BY TRYPANOSOMATIDS IN EXPERIMENTAL MURINE INFECTIONS
title_fullStr ULTRASTRUCTURAL STUDY ON TISSUE ALTERATIONS CAUSED BY TRYPANOSOMATIDS IN EXPERIMENTAL MURINE INFECTIONS
title_full_unstemmed ULTRASTRUCTURAL STUDY ON TISSUE ALTERATIONS CAUSED BY TRYPANOSOMATIDS IN EXPERIMENTAL MURINE INFECTIONS
title_sort ultrastructural study on tissue alterations caused by trypanosomatids in experimental murine infections
publisher Frontiers Media S.A.
series Frontiers in Public Health
issn 2296-2565
publishDate 2014-07-01
description The ultrastructural study in different tissues of mice experimentally infected with isolates of Trypanosoma evansi, Trypanosoma cruzi and Leishmania mexicana reveals changes in cardiac myocytes, skeletal muscle fibers and hepatic, adrenal, kidney and spleen cells. Some were cytoarchitectural changes and other consisted of necrosis. Alterations were also found in microvasculature.The mononuclear cell infiltrate included neutrophils, eosinophils and macrophages. This work shows that various mice tissues are important target for trypanosomatids.
topic Pathology
Ultraestructure
Murine Tissues
Experimental Infections
Trypanosomatids
url http://journal.frontiersin.org/Journal/10.3389/fpubh.2014.00075/full
work_keys_str_mv AT hectorjosefinol ultrastructuralstudyontissuealterationscausedbytrypanosomatidsinexperimentalmurineinfections
AT antonioeroschmangonzalez ultrastructuralstudyontissuealterationscausedbytrypanosomatidsinexperimentalmurineinfections
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