miR-128 Regulates Tumor Cell CD47 Expression and Promotes Anti-tumor Immunity in Pancreatic Cancer

miR-128 Regulates Tumor Cell CD47 Expression and Promotes Anti-tumor Immunity in Pancreatic Cancer

Pancreatic adenocarcinoma (PDAC) is a highly fatal disease worldwide. MicroRNAs (miRNAs) could regulate the protein-coding RNAs related to tumor growth, invasion, and immune evasion. Therefore, the investigation of novel miRNAs may be helpful in the development of more effective therapies for PDAC....

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Bibliographic Details
Main Authors: Qing Xi, Ying Chen, Guang-Ze Yang, Jie-You Zhang, Li-Juan Zhang, Xiang-Dong Guo, Jing-Yi Zhao, Zhen-Yi Xue, Yan Li, Rongxin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
miR-128
pancreatic adenocarcinoma (PDAC)
zinc finger E-box-binding homeobox 1 (ZEB1)
cluster of differentiation 47 (CD47)
tumor immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00890/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00890/full

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