What Characteristics Confer Proteins the Ability to Induce Allergic Responses? IgE Epitope Mapping and Comparison of the Structure of Soybean 2S Albumins and Ara h 2

What Characteristics Confer Proteins the Ability to Induce Allergic Responses? IgE Epitope Mapping and Comparison of the Structure of Soybean 2S Albumins and Ara h 2

Ara h 2, a peanut 2S albumin, is associated with severe allergic reactions, but a homologous protein, soybean 2S albumin, is not recognized as an important allergen. Structural difference between these proteins might explain this clinical discrepancy. Therefore, we mapped sequential epitopes and com...

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Bibliographic Details
Main Authors: Youngshin Han, Jing Lin, Ludmilla Bardina, Galina A. Grishina, Chaeyoon Lee, Won Hee Seo, Hugh A. Sampson
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Molecules
Subjects:
Ara h 2
epitope mapping
peptide microarray
soybean
2S albumins
Online Access:http://www.mdpi.com/1420-3049/21/5/622

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