Large, long range tensile forces drive convergence during Xenopus blastopore closure and body axis elongation

Large, long range tensile forces drive convergence during Xenopus blastopore closure and body axis elongation

Indirect evidence suggests that blastopore closure during gastrulation of anamniotes, including amphibians such as Xenopus laevis, depends on circumblastoporal convergence forces generated by the marginal zone (MZ), but direct evidence is lacking. We show that explanted MZs generate tensile converge...

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Bibliographic Details
Main Authors: David R Shook, Eric M Kasprowicz, Lance A Davidson, Raymond Keller
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
biomechanics
force
convergent extension
gastrulation
blastopore closure
convergent thickening
Online Access:https://elifesciences.org/articles/26944

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