Metabolic memory in mitochondrial oxidative damage triggers diabetic retinopathy

Metabolic memory in mitochondrial oxidative damage triggers diabetic retinopathy

Abstract Background Diabetic retinopathy (DR) is a microvascular complication induced by high blood glucose. This study was conducted to investigate the effect of metabolic memory on mitochondrial oxidative damage-induced DR. Methods Rat retinal endothelial cells (rRECs) were isolated from SD rats a...

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Bibliographic Details
Main Authors: Zhaoge Wang, Haixia Zhao, Wenying Guan, Xin Kang, Xue Tai, Ying Shen
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Ophthalmology
Subjects:
Diabetic retinopathy
Metabolic memory
ROS
Mitochondria
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12886-018-0921-0

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