The novel SH3 domain protein Dlish/CG10933 mediates fat signaling in Drosophila by binding and regulating Dachs

Much of the Hippo and planar cell polarity (PCP) signaling mediated by the Drosophila protocadherin Fat depends on its ability to change the subcellular localization, levels and activity of the unconventional myosin Dachs. To better understand this process, we have performed a structure-function ana...

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Bibliographic Details
Main Authors: Yifei Zhang, Xing Wang, Hitoshi Matakatsu, Richard Fehon, Seth S Blair
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-10-01
Series:eLife
Subjects:
Fat
Online Access:https://elifesciences.org/articles/16624