Coenzyme Q10 protected against arsenite and enhanced the capacity of 2,3-dimercaptosuccinic acid to ameliorate arsenite-induced toxicity in mice

Coenzyme Q10 protected against arsenite and enhanced the capacity of 2,3-dimercaptosuccinic acid to ameliorate arsenite-induced toxicity in mice

Abstract Background Arsenic poisoning affects millions of people. The inorganic forms of arsenic are more toxic. Treatment for arsenic poisoning relies on chelation of extracellularly circulating arsenic molecules by 2,3-dimecaptosuccinic acid (DMSA). As a pharmacological intervention, DMSA is unabl...

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Bibliographic Details
Main Authors: Victoria K. Mwaeni, James N. Nyariki, Ngalla Jillani, George Omwenga, Mathew Ngugi, Alfred Orina Isaac
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Pharmacology and Toxicology
Subjects:
Ubiquinone
Organ metal damage
Glutathione
Inflammation
Immune response
Online Access:https://doi.org/10.1186/s40360-021-00484-z

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