Therapeutic applications of genetic code expansion
In nature, a limited, conservative set of amino acids are utilized to synthesize proteins. Genetic code expansion technique reassigns codons and incorporates noncanonical amino acids (ncAAs) through orthogonal aminoacyl-tRNA synthetase (aaRS)/tRNA pairs. The past decade has witnessed the rapid growt...
Main Authors: | Yujia Huang, Tao Liu |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2018-09-01
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Series: | Synthetic and Systems Biotechnology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405805X18300401 |
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