Extended tacrolimus release via the combination of lipid-based solid dispersion and HPMC hydrogel matrix tablets

Extended tacrolimus release via the combination of lipid-based solid dispersion and HPMC hydrogel matrix tablets

The objective of this study is to evaluate the feasibility of obtaining extended release of tacrolimus by a novel combination of lipid-based solid dispersion and matrix-type extended release tablet techniques. Tacrolimus solid dispersion was prepared using glycerylbehenate (Compritol® ATO888) and Pl...

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Bibliographic Details
Main Authors: Hui Xu, Li Liu, Xuehui Li, Junyuan Ma, Rui Liu, Shaoning Wang
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Asian Journal of Pharmaceutical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087618302617

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