Human papillomavirus and genome instability: from productive infection to cancer

Human papillomavirus and genome instability: from productive infection to cancer

Infection with high oncogenic risk human papillomavirus types is the etiological factor of cervical cancer and a major cause of other epithelial malignancies, including vulvar, vaginal, anal, penile and head and neck carcinomas. These agents affect epithelial homeostasis through the expression of sp...

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Bibliographic Details
Main Authors: Bruna Prati, Bruna Marangoni, Enrique Boccardo
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2018-09-01
Series:Clinics
Subjects:
HPV
Genomic Instability
E6
E7
Cervical Cancer
Synthetic Lethality
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000200320&lng=en&tlng=en

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