Primordial germ cell specification from embryonic stem cells.

BACKGROUND: Primordial germ cell (PGC) specification is the first crucial step in germ line development. However, owing to significant challenges regarding the in vivo system, such as the complex cellular environment and potential problems with embryo manipulation, it is desirable to generate embryo...

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Bibliographic Details
Main Authors: Wei Wei, Tingting Qing, Xin Ye, Haisong Liu, Donghui Zhang, Weifeng Yang, Hongkui Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2602984?pdf=render

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