How MCM loading and spreading specify eukaryotic DNA replication initiation sites [version 1; referees: 4 approved]
DNA replication origins strikingly differ between eukaryotic species and cell types. Origins are localized and can be highly efficient in budding yeast, are randomly located in early fly and frog embryos, which do not transcribe their genomes, and are clustered in broad (10-100 kb) non-transcribed z...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2016-08-01
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| Series: | F1000Research |
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| Online Access: | http://f1000research.com/articles/5-2063/v1 |