Differential role of dose and environment in initiating and intensifying neurotoxicity caused by MDMA in rats

Abstract Background MDMA causes serotonin (5-HT) syndrome immediately after administration and serotonergic injury in a few days or weeks. However, a serotonin syndrome is not always followed by serotonergic injury, indicating different mechanisms responsible for two adverse effects. The goal of pre...

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Bibliographic Details
Main Authors: Ibrahim M. Shokry, Connor J. Shields, John J. Callanan, Zhiyuan Ma, Rui Tao
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40360-019-0326-6

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