Differential role of dose and environment in initiating and intensifying neurotoxicity caused by MDMA in rats
Abstract Background MDMA causes serotonin (5-HT) syndrome immediately after administration and serotonergic injury in a few days or weeks. However, a serotonin syndrome is not always followed by serotonergic injury, indicating different mechanisms responsible for two adverse effects. The goal of pre...
Main Authors: | Ibrahim M. Shokry, Connor J. Shields, John J. Callanan, Zhiyuan Ma, Rui Tao |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-08-01
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Series: | BMC Pharmacology and Toxicology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40360-019-0326-6 |
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