Successful Treatment of Richter Transformation with Ibrutinib in a Patient with Chronic Lymphocytic Leukemia following Allogeneic Hematopoietic Stem Cell Transplant

Successful Treatment of Richter Transformation with Ibrutinib in a Patient with Chronic Lymphocytic Leukemia following Allogeneic Hematopoietic Stem Cell Transplant

Patients with chronic lymphocytic leukemia (CLL) who progress to Richter transformation (RT) have a poor prognosis. Multi-agent chemotherapy regimens do not have good response rates. There are few case reports on the use of ibrutinib in RT. Here, we present a patient who was heavily pretreated for C...

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Bibliographic Details
Main Authors: Samip Master, Cheri Leary, Amol Takalkar, James Coltelingam, Richard Mansour, Glenn M. Mills, Nebu Koshy
Format: Article
Language:English
Published: Karger Publishers 2017-06-01
Series:Case Reports in Oncology
Subjects:
Ibrutinib
Richter transformation
Chronic lymphocytic leukemia
Ibrutinib after allogeneic transplant
Online Access:http://www.karger.com/Article/FullText/477338

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