Renal dysfunction in Leishmaniasis and Chagas disease coinfection: a case report

• Main Authors: Cid Carlos Soares de Alcântara, Laís Regina Lacerda Santana, Priscila Dourado Evangelista, André Costa Teixeira, Geraldo Bezerra da Silva Junior, Elizabeth De Francesco Daher
• Format: Article
• Language: English
• Published: Universidade de São Paulo 2018-11-01
• Series: Revista do Instituto de Medicina Tropical de São Paulo
• Subjects: Leishmaniasis; Acute kidney injury; Glomerulonephritis; Chagas disease; Parasitic diseases; Cardiomyopathy
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652018005000508&lng=en&tlng=en

ABSTRACT Visceral leishmaniasis (VL) is an endemic parasitic disease frequently found in Northeast Brazil and may cause acute kidney injury (AKI) and glomerulonephritis. After appropriate treatment, renal function recovery may occur. We describe the rare case of a patient with VL, who developed severe AKI requiring dialysis and was subsequently diagnosed with Chagas disease coinfection. After specific treatment for VL, there was partial recovery of the renal function, followed by the onset of Chagas disease cardiomyopathy.