MicroRNA-205-5p inhibits three-dimensional spheroid proliferation of ErbB2-overexpressing breast epithelial cells through direct targeting of CLCN3

We previously reported that microRNA-205-5p (miR-205-5p) is significantly decreased in the ErbB2-overexpressing breast epithelial cell line MCF10A-ErbB2 compared with control cells. In this study, we identified a direct target of miR-205-5p, chloride voltage-gated channel 3 (CLCN3). CLCN3 expression...

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Bibliographic Details
Main Authors: Takayoshi Takeno, Takuya Hasegawa, Hiroki Hasegawa, Yasuyuki Ueno, Ryo Hamataka, Aya Nakajima, Junji Okubo, Koji Sato, Toshiyuki Sakamaki
Format: Article
Language:English
Published: PeerJ Inc. 2019-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/7799.pdf