Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression

Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression

Endotoxin-induced lung injury is one of the major causes of death induced by endotoxemia, however, few effective therapeutic options exist. Hydrogen inhalation has recently been shown to be an effective treatment for inflammatory lung injury, but the underlying mechanism is unknown. In the current s...

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Bibliographic Details
Main Authors: Qian Li, Liang Hu, Juan Li, Pan Yu, Fan Hu, Bing Wan, Miaomiao Xu, Huixian Cheng, Wanyou Yu, Liping Jiang, Yadan Shi, Jincan Li, Manlin Duan, Yun Long, Wen-Tao Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
hydrogen
sepsis
lung
Trx1
TF
MMP-9
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.625957/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.625957/full

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