Systemic Antibiotic and Nonsteroidal Anti-Inflammatory Drug Treatment Decreases the Level of Endogenous Angiogenic Vascular Endothelial Growth Factor in Inflamed Human Periapical Tissues

Systemic Antibiotic and Nonsteroidal Anti-Inflammatory Drug Treatment Decreases the Level of Endogenous Angiogenic Vascular Endothelial Growth Factor in Inflamed Human Periapical Tissues

Vascular endothelial growth factor (VEGF)-induced angiogenesis contributes to inflammatory bone resorption in humans. Widely documented antagonists to resorption include antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs). The purpose of this study was to investigate the effect of these d...

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Bibliographic Details
Main Authors: Aleksandra Palatyńska-Ulatowska, Marta Michalska, Anna Drelich, Aleksandra Sałagacka-Kubiak, Ewa Balcerczak, Bogusława Manowska, José Antonio Poli de Figueiredo
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Applied Sciences
Subjects:
endodontic treatment
periapical periodontitis
antibiotics
nonsteroidal anti-inflammatory drugs
polymerase chain reaction (PCR)
vascular endothelial growth factor
Online Access:https://www.mdpi.com/2076-3417/11/11/4976

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