Re-evaluation of nicotinic acetylcholine receptor in rat brain by a tissue-segment binding assay

Re-evaluation of nicotinic acetylcholine receptor in rat brain by a tissue-segment binding assay

Nicotinic acetylcholine receptors (nAChRs) of cerebral cortex and cerebellum of rats were evaluated by a radioligand binding assay, employing tissue segments or homogenates as materials. [3H]-epibatidine specifically bound to nAChRs in rat cortex or cerebellum, but the dissociation constants for [...

Full description

Bibliographic Details
Main Authors: Mao Hsien Wang, Hatsumi eYoshiki, Abu Syed Md Anisuzzaman, Junsuke eUwada, Atsushi eNishimune, Kung Shing Lee, Takanobu eTaniguchi, Ikunobu eMuramatsu
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-10-01
Series:Frontiers in Pharmacology
Subjects:
nicotinic receptor
tissue-segment binding
upregulation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00065/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00065/full

Similar Items