Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34<sup>+ </sup>acute myeloid leukemia cell lines and primary sorted CD34<sup>+ </sup>acute myeloid leukemia cells

Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34<sup>+ </sup>acute myeloid leukemia cell lines and primary sorted CD34<sup>+ </sup>acute myeloid leukemia cells

<p>Abstract</p> <p>Background</p> <p>Acute myeloid leukemia (AML) is an immunophenotypically heterogenous malignant disease, in which CD34 positivity is associated with poor prognosis. CD34<sup>+ </sup>AML cells are 10-15-fold more resistant to daunorubicin...

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Bibliographic Details
Main Authors: Huang Sheng-Shan, Long Zi-Jie, Zheng Fei-Meng, Xu Duo-Rong, Rao Jia, Wu Xing, Zhou Wei-Hua, Huang Ren-Wei, Liu Quentin
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/71

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