Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34<sup>+ </sup>acute myeloid leukemia cell lines and primary sorted CD34<sup>+ </sup>acute myeloid leukemia cells
<p>Abstract</p> <p>Background</p> <p>Acute myeloid leukemia (AML) is an immunophenotypically heterogenous malignant disease, in which CD34 positivity is associated with poor prognosis. CD34<sup>+ </sup>AML cells are 10-15-fold more resistant to daunorubicin...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-05-01
|
| Series: | Journal of Translational Medicine |
| Online Access: | http://www.translational-medicine.com/content/9/1/71 |