dMyc is required in retinal progenitors to prevent JNK-mediated retinal glial activation.

In the nervous system, glial cells provide crucial insulation and trophic support to neurons and are important for neuronal survival. In reaction to a wide variety of insults, glial cells respond with changes in cell morphology and metabolism to allow repair. Additionally, these cells can acquire mi...

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Bibliographic Details
Main Authors: Lígia Tavares, Andreia Correia, Marília A Santos, João B Relvas, Paulo S Pereira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5360344?pdf=render