Simple Synthesis of Modafinil Derivatives and Their Anti-inflammatory Activity

Simple Synthesis of Modafinil Derivatives and Their Anti-inflammatory Activity

Simple synthesis of modafinil derivatives and their biological activity are described. The key synthetic strategies involve substitution and coupling reactions. We determined the anti-inflammatory effects of modafinil derivatives in cultured BV2 cells by measuring the inhibition of nitrite productio...

Full description

Bibliographic Details
Main Authors: Mankil Jung, Seikwan Oh, Eunyoung Lim, Jee-Young Son, Yeonju Lee, Jae-Chul Jung
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Molecules
Subjects:
modafinil
anti-inflammation
nitric oxide
<em>S</em>-alkylation
coupling reaction
Online Access:http://www.mdpi.com/1420-3049/17/9/10446

Internet

http://www.mdpi.com/1420-3049/17/9/10446

Similar Items