Alzheimer’s Disease: A Thermodynamic Perspective
Alzheimer’s disease is investigated using a thermodynamic approach based on ion fluxes across the neuronal membrane. Our study indicates that the onset of Alzheimer’s may be aided by a hyperpolarization of this membrane, because hyperpolarization-activated cyclic nucleotide gated HCN channels 1–4 co...
Main Authors: | Umberto Lucia, Giulia Grisolia, Thomas S. Deisboeck |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
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Series: | Applied Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3417/10/21/7562 |
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