Baicalin Attenuates High Fat Diet-Induced Obesity and Liver Dysfunction: Dose-Response and Potential Role of CaMKKβ/AMPK/ACC Pathway

Baicalin Attenuates High Fat Diet-Induced Obesity and Liver Dysfunction: Dose-Response and Potential Role of CaMKKβ/AMPK/ACC Pathway

Background/Aims: Obesity-associated fatty liver disease affects millions of individuals. This study aimed to evaluate the therapeutic effects of baicalin to treat obesity and fatty liver in high fat diet-induced obese mice, and to study the potential molecular mechanisms. Methods: High fat diet-indu...

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Bibliographic Details
Main Authors: Youli Xi, Miaozong Wu, Hongxia Li, Siqi Dong, Erfei Luo, Mingbo Gu, Xiao Shen, Yabo Jiang, Yaqun Liu, Hua Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Baicalin
Obesity
AMP-activated protein kinase
Acetyl-CoA carboxylase
Liver dysfunction
Ca2+/CaM-dependent protein kinase kinase β
Online Access:http://www.karger.com/Article/FullText/374037

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