Efficacy of 3 treatments for cervical endometriosis: clinical analysis of 106 cases

• Main Authors: YANG Jun, LONG Xin, YAN Li, ZHOU Deping
• Format: Article
• Language: zho
• Published: Editorial Office of Journal of Third Military Medical University 2020-12-01
• Series: Di-san junyi daxue xuebao
• Subjects: cervix; endometriosis; therapy
• Online Access: http://aammt.tmmu.edu.cn/Upload/rhtml/202008149.htm

Objective To evaluate the clinical efficacy of 3 treatments for cervical endometriosis. Methods Clinical data of 106 patients with cervical endometriosis treated in our center from January 2013 to March 2019 were collected and retrospectively analyzed. According to the treatments, they were assigned into yttrium aluminum garnet (YAG) laser group (n=44, laser group), transvaginal administration of policresulen suppositories group (n=37, medication group) and YAG laser along with oral contraceptive group (n=25, Diane-35, combination group). The clinical efficacy and adverse effects were evaluated and compared among the 3 groups during the 6~12 months' follow-up. Results ① The total effective rates were 93.18% (41/44), 78.38% (29/37) and 96.00% (24/25), respectively, in the laser, medication and combination groups, with statistical difference among them (Chi-square=6.076, P < 0.05). ② The original lesion size showed no effect on clinical efficacy both in the laser group (Chi-square=-1.538, P>0.05) and the combination group (Chi-square=-1.239, P>0.05). In the medication group, the patients with lesions involving ≤2 quadrants had a higher recovery rate than those with >2 quadrants (Chi-square=-2.796, P < 0.01). ③ In the laser group, the recovery rate of the patients with simple cervical endometriosis was higher than that of those with other parts of endometriosis (Z=-2.124, P < 0.05). But, the rate was not affected by whether involving other parts or not in the medication (Z=-1.337, P>0.05) and combination groups (Z=-0.873, P>0.05). ④ During the follow-up of 6~12 months, no recurrence was found in the combination group. The size of original lesion and involvement of other parts had no effect on the recurrence rate in the laser group (P>0.05). In the medication group, the patients with lesions of >2 quadrants or with other parts of endometriosis had higher recurrence rate (P < 0.05). Conclusion Size of cervical lesions and whether involved with other parts of endometriosis should be considered when choosing different treatment methods for cervical endometriosis.