IL-1 signal affects both protection and pathogenesis of virus-induced chronic CNS demyelinating disease

<p>Abstract</p> <p>Background</p> <p>Theiler’s virus infection induces chronic demyelinating disease in mice and has been investigated as an infectious model for multiple sclerosis (MS). IL-1 plays an important role in the pathogenesis of both the autoimmune disease mod...

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Bibliographic Details
Main Authors: Kim Byung S, Jin Young-Hee, Meng Liping, Hou Wanqiu, Kang Hyun, Park Hey, Koh Chang-Sung
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Journal of Neuroinflammation
Subjects:
CNS
Online Access:http://www.jneuroinflammation.com/content/9/1/217