Maltoma of Thyroid: A Rare Thyroid Tumour
Introduction. Primary thyroid lymphomas constitute up to 5% of all thyroid malignancies and can be divided into non-Hodgkin’s lymphomas (NHLs) of B- and T-cell types, as well as Hodgkin’s lymphomas. Mucosa-associated lymphoid tissue (MALT) lymphomas are a relatively recently recognized subset of B-...
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doaj-9aea40dc0b98478082df7f86b63aebf12020-11-24T22:51:49ZengHindawi LimitedCase Reports in Otolaryngology2090-67652090-67732013-01-01201310.1155/2013/740241740241Maltoma of Thyroid: A Rare Thyroid TumourNavisha Latheef0Vijendra Shenoy1M. Panduranga Kamath2Mahesh Chandra Hegde3A. Raghavendra Rao4Department of E.N.T-Head and Neck Surgery, Kasturba Medical College, Manipal University, Mangalore 575001, IndiaDepartment of E.N.T-Head and Neck Surgery, Kasturba Medical College, Manipal University, Mangalore 575001, IndiaDepartment of E.N.T-Head and Neck Surgery, Kasturba Medical College, Manipal University, Mangalore 575001, IndiaDepartment of E.N.T-Head and Neck Surgery, Kasturba Medical College, Manipal University, Mangalore 575001, IndiaDepartment of E.N.T-Head and Neck Surgery, Kasturba Medical College, Manipal University, Mangalore 575001, IndiaIntroduction. Primary thyroid lymphomas constitute up to 5% of all thyroid malignancies and can be divided into non-Hodgkin’s lymphomas (NHLs) of B- and T-cell types, as well as Hodgkin’s lymphomas. Mucosa-associated lymphoid tissue (MALT) lymphomas are a relatively recently recognized subset of B-cell NHLs, and they are listed as extranodal marginal zone lymphomas according to the revised European-American lymphoma classification. Case Report. We report an uncommon case of a 44-year-old man, who noted a painless, growing mass on right side of his neck of the three-month duration. Thyroid profile was within normal limits. FNAC showed lymphocytic thyroiditis. The patient underwent a right hemithyroidectomy. The histologic examination and the immunohistochemistry showed an extra nodal marginal B-cell type maltoma (malt lymphoma). CHOP chemotherapy with rituximab was given. The clinical course has been favourable in the first year of followup, with no evidence of local or systemic recurrence of the disease. Discussion. Marginal zone lymphoma encompasses a heterogeneous group of B-cell tumours that variously arise within the lymph nodes, spleen, or extranodal tissues. A case of maltoma of thyroid is presented for its rarity and diagnostic dilemmas. Conclusion. Maltomas are slow-growing lymphomas. The optimal treatment and followup of patients with thyroid maltomas remain controversial at present.http://dx.doi.org/10.1155/2013/740241 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Navisha Latheef Vijendra Shenoy M. Panduranga Kamath Mahesh Chandra Hegde A. Raghavendra Rao |
spellingShingle |
Navisha Latheef Vijendra Shenoy M. Panduranga Kamath Mahesh Chandra Hegde A. Raghavendra Rao Maltoma of Thyroid: A Rare Thyroid Tumour Case Reports in Otolaryngology |
author_facet |
Navisha Latheef Vijendra Shenoy M. Panduranga Kamath Mahesh Chandra Hegde A. Raghavendra Rao |
author_sort |
Navisha Latheef |
title |
Maltoma of Thyroid: A Rare Thyroid Tumour |
title_short |
Maltoma of Thyroid: A Rare Thyroid Tumour |
title_full |
Maltoma of Thyroid: A Rare Thyroid Tumour |
title_fullStr |
Maltoma of Thyroid: A Rare Thyroid Tumour |
title_full_unstemmed |
Maltoma of Thyroid: A Rare Thyroid Tumour |
title_sort |
maltoma of thyroid: a rare thyroid tumour |
publisher |
Hindawi Limited |
series |
Case Reports in Otolaryngology |
issn |
2090-6765 2090-6773 |
publishDate |
2013-01-01 |
description |
Introduction. Primary thyroid lymphomas constitute up to 5% of all thyroid malignancies and can be divided into non-Hodgkin’s lymphomas (NHLs) of B- and T-cell types, as well as Hodgkin’s lymphomas. Mucosa-associated lymphoid tissue (MALT) lymphomas are a relatively recently recognized subset of B-cell NHLs, and they are listed as extranodal marginal zone lymphomas according to the revised European-American lymphoma classification. Case Report. We report an uncommon case of a 44-year-old man, who noted a painless, growing mass on right side of his neck of the three-month duration. Thyroid profile was within normal limits. FNAC showed lymphocytic thyroiditis. The patient underwent a right hemithyroidectomy. The histologic examination and the immunohistochemistry showed an extra nodal marginal B-cell type maltoma (malt lymphoma). CHOP chemotherapy with rituximab was given. The clinical course has been favourable in the first year of followup, with no evidence of local or systemic recurrence of the disease. Discussion. Marginal zone lymphoma encompasses a heterogeneous group of B-cell tumours that variously arise within the lymph nodes, spleen, or extranodal tissues. A case of maltoma of thyroid is presented for its rarity and diagnostic dilemmas. Conclusion. Maltomas are slow-growing lymphomas. The optimal treatment and followup of patients with thyroid maltomas remain controversial at present. |
url |
http://dx.doi.org/10.1155/2013/740241 |
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