Maltoma of Thyroid: A Rare Thyroid Tumour

Introduction. Primary thyroid lymphomas constitute up to 5% of all thyroid malignancies and can be divided into non-Hodgkin’s lymphomas (NHLs) of B- and T-cell types, as well as Hodgkin’s lymphomas. Mucosa-associated lymphoid tissue (MALT) lymphomas are a relatively recently recognized subset of B-...

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Main Authors: Navisha Latheef, Vijendra Shenoy, M. Panduranga Kamath, Mahesh Chandra Hegde, A. Raghavendra Rao
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2013/740241
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spelling doaj-9aea40dc0b98478082df7f86b63aebf12020-11-24T22:51:49ZengHindawi LimitedCase Reports in Otolaryngology2090-67652090-67732013-01-01201310.1155/2013/740241740241Maltoma of Thyroid: A Rare Thyroid TumourNavisha Latheef0Vijendra Shenoy1M. Panduranga Kamath2Mahesh Chandra Hegde3A. Raghavendra Rao4Department of E.N.T-Head and Neck Surgery, Kasturba Medical College, Manipal University, Mangalore 575001, IndiaDepartment of E.N.T-Head and Neck Surgery, Kasturba Medical College, Manipal University, Mangalore 575001, IndiaDepartment of E.N.T-Head and Neck Surgery, Kasturba Medical College, Manipal University, Mangalore 575001, IndiaDepartment of E.N.T-Head and Neck Surgery, Kasturba Medical College, Manipal University, Mangalore 575001, IndiaDepartment of E.N.T-Head and Neck Surgery, Kasturba Medical College, Manipal University, Mangalore 575001, IndiaIntroduction. Primary thyroid lymphomas constitute up to 5% of all thyroid malignancies and can be divided into non-Hodgkin’s lymphomas (NHLs) of B- and T-cell types, as well as Hodgkin’s lymphomas. Mucosa-associated lymphoid tissue (MALT) lymphomas are a relatively recently recognized subset of B-cell NHLs, and they are listed as extranodal marginal zone lymphomas according to the revised European-American lymphoma classification. Case Report. We report an uncommon case of a 44-year-old man, who noted a painless, growing mass on right side of his neck of the three-month duration. Thyroid profile was within normal limits. FNAC showed lymphocytic thyroiditis. The patient underwent a right hemithyroidectomy. The histologic examination and the immunohistochemistry showed an extra nodal marginal B-cell type maltoma (malt lymphoma). CHOP chemotherapy with rituximab was given. The clinical course has been favourable in the first year of followup, with no evidence of local or systemic recurrence of the disease. Discussion. Marginal zone lymphoma encompasses a heterogeneous group of B-cell tumours that variously arise within the lymph nodes, spleen, or extranodal tissues. A case of maltoma of thyroid is presented for its rarity and diagnostic dilemmas. Conclusion. Maltomas are slow-growing lymphomas. The optimal treatment and followup of patients with thyroid maltomas remain controversial at present.http://dx.doi.org/10.1155/2013/740241
collection DOAJ
language English
format Article
sources DOAJ
author Navisha Latheef
Vijendra Shenoy
M. Panduranga Kamath
Mahesh Chandra Hegde
A. Raghavendra Rao
spellingShingle Navisha Latheef
Vijendra Shenoy
M. Panduranga Kamath
Mahesh Chandra Hegde
A. Raghavendra Rao
Maltoma of Thyroid: A Rare Thyroid Tumour
Case Reports in Otolaryngology
author_facet Navisha Latheef
Vijendra Shenoy
M. Panduranga Kamath
Mahesh Chandra Hegde
A. Raghavendra Rao
author_sort Navisha Latheef
title Maltoma of Thyroid: A Rare Thyroid Tumour
title_short Maltoma of Thyroid: A Rare Thyroid Tumour
title_full Maltoma of Thyroid: A Rare Thyroid Tumour
title_fullStr Maltoma of Thyroid: A Rare Thyroid Tumour
title_full_unstemmed Maltoma of Thyroid: A Rare Thyroid Tumour
title_sort maltoma of thyroid: a rare thyroid tumour
publisher Hindawi Limited
series Case Reports in Otolaryngology
issn 2090-6765
2090-6773
publishDate 2013-01-01
description Introduction. Primary thyroid lymphomas constitute up to 5% of all thyroid malignancies and can be divided into non-Hodgkin’s lymphomas (NHLs) of B- and T-cell types, as well as Hodgkin’s lymphomas. Mucosa-associated lymphoid tissue (MALT) lymphomas are a relatively recently recognized subset of B-cell NHLs, and they are listed as extranodal marginal zone lymphomas according to the revised European-American lymphoma classification. Case Report. We report an uncommon case of a 44-year-old man, who noted a painless, growing mass on right side of his neck of the three-month duration. Thyroid profile was within normal limits. FNAC showed lymphocytic thyroiditis. The patient underwent a right hemithyroidectomy. The histologic examination and the immunohistochemistry showed an extra nodal marginal B-cell type maltoma (malt lymphoma). CHOP chemotherapy with rituximab was given. The clinical course has been favourable in the first year of followup, with no evidence of local or systemic recurrence of the disease. Discussion. Marginal zone lymphoma encompasses a heterogeneous group of B-cell tumours that variously arise within the lymph nodes, spleen, or extranodal tissues. A case of maltoma of thyroid is presented for its rarity and diagnostic dilemmas. Conclusion. Maltomas are slow-growing lymphomas. The optimal treatment and followup of patients with thyroid maltomas remain controversial at present.
url http://dx.doi.org/10.1155/2013/740241
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