Effects of bevacizumab on endoplasmic reticulum stress in hypoxic retinal pigment epithelial cells.

To investigate the effects of bevacizumab on endoplasmic reticulum (ER) stress in human retinal pigment epithelial (RPE) cells cultured under hypoxic conditions.RPE cells (ARPE-19) were cultured under hypoxic conditions (1% O2) with or without bevacizumab (0.3125 mg/mL) for 24 and 48 h. Cell viabili...

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Bibliographic Details
Main Authors: Joo-Hee Park, Moosang Kim, Jong-Hyun Oh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5462411?pdf=render

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