Dopaminergic cell damage and vulnerability to MPTP in Pink1 knockdown zebrafish

The functions of PTEN (phosphatase/tensin homolog)-induced putative kinase (PINK1), which is mutated in early-onset Parkinson's disease, are poorly understood. We characterized a PINK1 antibody and found colocalization of PINK1-like immunoreactivity with aminergic markers. We inactivated transl...

Full description

Bibliographic Details
Main Authors: Ville Sallinen, Juha Kolehmainen, Madhusmita Priyadarshini, Gabija Toleikyte, Yu-Chia Chen, Pertti Panula
Format: Article
Language:English
Published: Elsevier 2010-10-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611000197X