CryoET structures of immature HIV Gag reveal six-helix bundle

Mendonça et al. determine the structures of both in vitro assemblies of the HIV structural precursor protein Gag and Gag viral-like particles (VLPs) to 4.2 Å and 4.5 Å resolutions, using cryo-electron tomography and subtomogram averaging. This study provides insights into the future development of s...

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Bibliographic Details
Main Authors: Luiza Mendonça, Dapeng Sun, Jiying Ning, Jiwei Liu, Abhay Kotecha, Mateusz Olek, Thomas Frosio, Xiaofeng Fu, Benjamin A. Himes, Alex B. Kleinpeter, Eric O. Freed, Jing Zhou, Christopher Aiken, Peijun Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01999-1