IGF-I activates caspases 3/7, 8 and 9 but does not induce cell death in colorectal cancer cells

IGF-I activates caspases 3/7, 8 and 9 but does not induce cell death in colorectal cancer cells

<p>Abstract</p> <p>Background</p> <p>Colorectal cancer is the third most common cancer in the western world. Chemotherapy is often ineffective to treat the advanced colorectal cancers due to the chemo-resistance. A major contributor to chemo-resistance is tumour-derived...

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Bibliographic Details
Main Authors: Seifalian Alexander M, Fuller Barry, Sales Kevin M, Bolvin Capucine, Yang Shi Yu, Winslet Marc C
Format: Article
Language:English
Published: BMC 2009-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/158

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