Identification of a binding site for ASF/SF2 on an RNA fragment derived from the hepatitis delta virus genome.

The hepatitis delta virus (HDV) is a small (~1700 nucleotides) RNA pathogen which encodes only one open reading frame. Consequently, HDV is dependent on host proteins to replicate its RNA genome. Recently, we reported that ASF/SF2 binds directly and specifically to an HDV-derived RNA fragment which...

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Bibliographic Details
Main Authors: Dorota Sikora, Dajiang Zhang, Teodora Bojic, Yasnee Beeharry, Ali Tanara, Martin Pelchat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3548785?pdf=render