MicroRNA-200a Promotes Phagocytosis of Macrophages and Suppresses Cell Proliferation, Migration, and Invasion in Nasopharyngeal Carcinoma by Targeting CD47
Nasopharyngeal carcinoma (NPC) causes severe oncogenic lesions in the nasopharynx. CD47, a transmembrane integrin-associated protein, plays a key role in the ability of tumor cells to escape phagocytosis, working as an immune checkpoint in the immune response. Besides this role, CD47 has been report...
Main Authors: | Yunteng Zhao, Xiaoxiao Yu, Haocheng Tang, Ri Han, Xianwen Wang, Jianqi Wang, Ke Wang, Gang Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2020-01-01
|
Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2020/3723781 |
Similar Items
-
Establishment of an organoid model of nasopharyngeal carcinoma and its in vitro chemosensitivity profile
by: WANG Xianwen, et al.
Published: (2020-07-01) -
Luteolin promotes macrophage-mediated phagocytosis by inhibiting CD47 pyroglutamation
by: Zhiqiang Li, et al.
Published: (2021-08-01) -
Role of the CD47/SIRPα-interaction in regulation of macrophage phagocytosis
by: Olsson, Mattias
Published: (2008) -
Expression Characteristics of miR-10b in Nasopharyngeal Carcinoma
by: Gang Li, et al.
Published: (2015-01-01) -
Attenuation of CD47-SIRPα Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis
by: Kulthida Vaeteewoottacharn, et al.
Published: (2019-02-01)