Study on orally delivered paclitaxel nanocrystals: modification, characterization and activity in the gastrointestinal tract

Drug nanocrystals (NCs) can improve the solubility and bioavailability of insoluble drugs for oral administration. However, the biocompatibility and mechanisms of transmittance of drug NCs through the intestinal epithelial tissue are still not well understood. In this work, the physico-chemical prop...

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Bibliographic Details
Main Authors: Runcong Liu, Ya-Nan Chang, Gengmei Xing, Min Li, Yuliang Zhao
Format: Article
Language:English
Published: The Royal Society 2017-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170753