The application of tetracycline-regulated gene expression systems in the validation of novel drug targets in Mycobacterium tuberculosis
Although efforts to identify novel therapies for the treatment of tuberculosis (TB) have led to the identification of several promising drug candidates, the identification of high-quality hits from conventional whole-cell screens remains disappointingly low. The elucidation of the genome sequence of...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-08-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00812/full |