Reversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coli

Genetic circuits can be built with bifunctional dynamic regulation of gene expression. Here the authors design a thermosensitive switch for spatial and temporal control of colony pattern, cell shape and polymer production.

Bibliographic Details
Main Authors:	Xuan Wang, Jia-Ning Han, Xu Zhang, Yue-Yuan Ma, Yina Lin, Huan Wang, Dian-Jie Li, Tao-Ran Zheng, Fu-Qing Wu, Jian-Wen Ye, Guo-Qiang Chen
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-03-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-021-21654-x

id	doaj-9a7310b9724846f194fd87d843879935
record_format	Article
spelling	doaj-9a7310b9724846f194fd87d8438799352021-03-11T11:33:31ZengNature Publishing GroupNature Communications2041-17232021-03-0112111310.1038/s41467-021-21654-xReversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coliXuan Wang0Jia-Ning Han1Xu Zhang2Yue-Yuan Ma3Yina Lin4Huan Wang5Dian-Jie Li6Tao-Ran Zheng7Fu-Qing Wu8Jian-Wen Ye9Guo-Qiang Chen10Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua UniversityCenter for Synthetic and Systems Biology, School of Life Sciences, Tsinghua UniversityCenter for Synthetic and Systems Biology, School of Life Sciences, Tsinghua UniversityCenter for Synthetic and Systems Biology, School of Life Sciences, Tsinghua UniversityCenter for Synthetic and Systems Biology, School of Life Sciences, Tsinghua UniversityCenter for Synthetic and Systems Biology, School of Life Sciences, Tsinghua UniversitySchool of Physics, Peking UniversityCenter for Synthetic and Systems Biology, School of Life Sciences, Tsinghua UniversityCenter for Synthetic and Systems Biology, School of Life Sciences, Tsinghua UniversityCenter for Synthetic and Systems Biology, School of Life Sciences, Tsinghua UniversityCenter for Synthetic and Systems Biology, School of Life Sciences, Tsinghua UniversityGenetic circuits can be built with bifunctional dynamic regulation of gene expression. Here the authors design a thermosensitive switch for spatial and temporal control of colony pattern, cell shape and polymer production.https://doi.org/10.1038/s41467-021-21654-x
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Xuan Wang Jia-Ning Han Xu Zhang Yue-Yuan Ma Yina Lin Huan Wang Dian-Jie Li Tao-Ran Zheng Fu-Qing Wu Jian-Wen Ye Guo-Qiang Chen
spellingShingle	Xuan Wang Jia-Ning Han Xu Zhang Yue-Yuan Ma Yina Lin Huan Wang Dian-Jie Li Tao-Ran Zheng Fu-Qing Wu Jian-Wen Ye Guo-Qiang Chen Reversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coli Nature Communications
author_facet	Xuan Wang Jia-Ning Han Xu Zhang Yue-Yuan Ma Yina Lin Huan Wang Dian-Jie Li Tao-Ran Zheng Fu-Qing Wu Jian-Wen Ye Guo-Qiang Chen
author_sort	Xuan Wang
title	Reversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coli
title_short	Reversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coli
title_full	Reversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coli
title_fullStr	Reversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coli
title_full_unstemmed	Reversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coli
title_sort	reversible thermal regulation for bifunctional dynamic control of gene expression in escherichia coli
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2021-03-01
description	Genetic circuits can be built with bifunctional dynamic regulation of gene expression. Here the authors design a thermosensitive switch for spatial and temporal control of colony pattern, cell shape and polymer production.
url	https://doi.org/10.1038/s41467-021-21654-x
work_keys_str_mv	AT xuanwang reversiblethermalregulationforbifunctionaldynamiccontrolofgeneexpressioninescherichiacoli AT jianinghan reversiblethermalregulationforbifunctionaldynamiccontrolofgeneexpressioninescherichiacoli AT xuzhang reversiblethermalregulationforbifunctionaldynamiccontrolofgeneexpressioninescherichiacoli AT yueyuanma reversiblethermalregulationforbifunctionaldynamiccontrolofgeneexpressioninescherichiacoli AT yinalin reversiblethermalregulationforbifunctionaldynamiccontrolofgeneexpressioninescherichiacoli AT huanwang reversiblethermalregulationforbifunctionaldynamiccontrolofgeneexpressioninescherichiacoli AT dianjieli reversiblethermalregulationforbifunctionaldynamiccontrolofgeneexpressioninescherichiacoli AT taoranzheng reversiblethermalregulationforbifunctionaldynamiccontrolofgeneexpressioninescherichiacoli AT fuqingwu reversiblethermalregulationforbifunctionaldynamiccontrolofgeneexpressioninescherichiacoli AT jianwenye reversiblethermalregulationforbifunctionaldynamiccontrolofgeneexpressioninescherichiacoli AT guoqiangchen reversiblethermalregulationforbifunctionaldynamiccontrolofgeneexpressioninescherichiacoli
_version_	1724225410488598528

Reversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coli

Similar Items