INTRAPLEURAL USE OF STREPTOKINASE

INTRAPLEURAL USE OF STREPTOKINASE

BACKGROUND Intrapleural application of streptokinase (SK) is an old and somewhat forgotten method oftreatment of complicated pleural effusions. In a selected group of cases, SK can successfullyreplace more aggressive surgical procedures. METHODS A retrospective analysis of all intrapleural SK applic...

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Main Authors: Tomaž Štupnik, Stanko Vidmar, Janez Eržen, Mihael Sok
Format: Article
Language:English
Published: Slovenian Medical Association 2008-04-01
Series:Zdravniški Vestnik
Online Access:http://vestnik.szd.si/index.php/ZdravVest/article/view/471
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spelling doaj-9a6cf0ee063c419891192de153b080dd2020-11-24T21:06:56ZengSlovenian Medical AssociationZdravniški Vestnik1318-03471581-02242008-04-01774363INTRAPLEURAL USE OF STREPTOKINASETomaž ŠtupnikStanko VidmarJanez ErženMihael SokBACKGROUND Intrapleural application of streptokinase (SK) is an old and somewhat forgotten method oftreatment of complicated pleural effusions. In a selected group of cases, SK can successfullyreplace more aggressive surgical procedures. METHODS A retrospective analysis of all intrapleural SK applications at our department between2004 and 2007 was performed. RESULTS 14 patients met the study inclusion criteria: 7 parapneumonic effusions, 5 residual hemothoracesand 2 loculated malignant effusions.Significant increase of the drained volume with notable radiological and clinical improvementfollowed the applications of 500,000 IU of SK in all patients and 9 patients (64 %)were spared the painful thoracotomy. CONCLUSIONS Our data supports the evidence on high efficiency of the intrapleural fibrinolysis with SK ina selected population of complicated pleural effusionshttp://vestnik.szd.si/index.php/ZdravVest/article/view/471
collection DOAJ
language English
format Article
sources DOAJ
author Tomaž Štupnik
Stanko Vidmar
Janez Eržen
Mihael Sok
spellingShingle Tomaž Štupnik
Stanko Vidmar
Janez Eržen
Mihael Sok
INTRAPLEURAL USE OF STREPTOKINASE
Zdravniški Vestnik
author_facet Tomaž Štupnik
Stanko Vidmar
Janez Eržen
Mihael Sok
author_sort Tomaž Štupnik
title INTRAPLEURAL USE OF STREPTOKINASE
title_short INTRAPLEURAL USE OF STREPTOKINASE
title_full INTRAPLEURAL USE OF STREPTOKINASE
title_fullStr INTRAPLEURAL USE OF STREPTOKINASE
title_full_unstemmed INTRAPLEURAL USE OF STREPTOKINASE
title_sort intrapleural use of streptokinase
publisher Slovenian Medical Association
series Zdravniški Vestnik
issn 1318-0347
1581-0224
publishDate 2008-04-01
description BACKGROUND Intrapleural application of streptokinase (SK) is an old and somewhat forgotten method oftreatment of complicated pleural effusions. In a selected group of cases, SK can successfullyreplace more aggressive surgical procedures. METHODS A retrospective analysis of all intrapleural SK applications at our department between2004 and 2007 was performed. RESULTS 14 patients met the study inclusion criteria: 7 parapneumonic effusions, 5 residual hemothoracesand 2 loculated malignant effusions.Significant increase of the drained volume with notable radiological and clinical improvementfollowed the applications of 500,000 IU of SK in all patients and 9 patients (64 %)were spared the painful thoracotomy. CONCLUSIONS Our data supports the evidence on high efficiency of the intrapleural fibrinolysis with SK ina selected population of complicated pleural effusions
url http://vestnik.szd.si/index.php/ZdravVest/article/view/471
work_keys_str_mv AT tomazstupnik intrapleuraluseofstreptokinase
AT stankovidmar intrapleuraluseofstreptokinase
AT janezerzen intrapleuraluseofstreptokinase
AT mihaelsok intrapleuraluseofstreptokinase
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