Detection of K76T Mutation in pfcrt Gene as an Applicable Ge-netic Marker for Prediction of Chloroquine Resistant falciparum Malaria in Isolates from an Endemic District of Iran

Detection of K76T Mutation in pfcrt Gene as an Applicable Ge-netic Marker for Prediction of Chloroquine Resistant falciparum Malaria in Isolates from an Endemic District of Iran

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Background: This study investigated the association between pfcrt, T76 allele and chloroquine resistance in patients with falciparum malaria. Molecular assays for point mutations on drugs resistance-related genes are applied tools for monitoring emerging resistance and surveillance malaria control...

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Bibliographic Details
Main Authors: AR Esmaeili Rastaghi, M Nateghpou, M Assmar, MR Razavi, H Kanbara, H Uemura, SR Naddaf, H Keshavarz, A Raeisi, M Mohebali
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2008-06-01
Series:Iranian Journal of Parasitology
Subjects:
Plasmodium falciparum
chloroquine resistance
pfcrt
K76T
Iran
Online Access:https://ijpa.tums.ac.ir/index.php/ijpa/article/view/62
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